Ismene L. Petrakis, MD - PTSD: National Center for PTSD
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PTSD: National Center for PTSD


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Ismene L. Petrakis, MD

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Ismene L. Petrakis, MD

Ismene L. Petrakis, MD

Acting Deputy Director

Clinical Neurosciences Division

See staff directory for contact information.

Academic Appointment

  • Yale University School of Medicine, Professor of Psychiatry


  • Resident in Psychiatry, Yale University School of Medicine, 1988-1991
  • Intern, Norwalk Hospital, Department of Internal Medicine, 1987-1988
  • University of Pittsburgh, M.D. 1987
  • Northwestern University, B.A. 1983

Expertise and Interests

  • PTSD with Comorbid Alcohol Use Disorder
  • PTSD with Comorbid Opioid Use Disorder
  • Neurobiology of PTSD with Comorbid Substance Use Disorders

Membership in Professional Societies

  • Pain Management and Opioid Safety in the Veterans Health Administration, "Effective Management of Pain and Addiction: Strategies to Improve Opioid Safety" State of the Art (SOTA) Planning Committee Member
  • Member, American Association of Directors of Psychiatric Residency Training
  • Associate Editor, Case-Series for American Journal of Addictions
  • Member, Editorial Board for Addictive Disorders & Their Treatment
  • Chair, American Academy of Addiction Psychiatry (AAAP) Area Directors, Program Committee
  • Co-Editor, Journal of Addiction Medicine

Awards and Honors

  • The Hedwig van Ameringen Executive Leadership in Academic Medicine (ELAM)
  • National Acupuncture Detoxification Association (NADA) Award for Vision and Leadership
  • The Stephen Fleck Faculty Award as exemplary physician and clinical teacher, Yale University School of Medicine

Selected Publications

Meshberg-Cohen, S., Black, A.C., DeViva, J.C., Petrakis, I.L., & Rosen, M.I. (2019). Trauma treatment for veterans in buprenorphine maintenance treatment for opioid use disorder. Addict Behav; 89:29-34.

Verplaetse, T., Ralevski, R., Roberts, W., Gueorguieva, R., McKee, S., & Petrakis, I. (2019). Alcohol abstainer status and prazosin treatment in association with change in PTSD symptoms in veterans with comorbid AUD and PTSD. Alcoholism: Clinical and Experimental Research, 43(4):741-746.

Petrakis, I.L., & Simpson, T.L. (2017). Posttraumatic stress disorder and alcohol use disorder: A critical review of pharmacologic treatments. Alcoholism: Clinical and Experimental Research, 41(2):226-237.

Simpson, T.L., Lehavot, K., & Petrakis, I.L. (2017). No wrong doors: Findings from a critical review of behavioral randomized clinical trials for individuals with co-occurring alcohol/drug problems and PTSD. Alcoholism: Clinical and Experimental Research, 41(4):681-702.

Petrakis, I.L., Desai, N., Gueorguieva, R., Arias, A., O'Brien, E., Jane, J.S., Sevarino, K., Southwick, S., & Ralevski, E.(2016). Prazosin for veterans with posttraumatic stress disorder (PTSD) and co-morbid alcohol dependence: A clinical trial. Alcoholism: Clinical & Experimental Research, 40(1):178-86.

Members of the press interested in scheduling an interview please see the contact for the media page.

PTSD Information Voice Mail: (802) 296-6300
Also see: VA Mental Health